Analysis of Zoledronic Acid (IC I-524A)

Bisphosphonates are the medicines used to treat osteoporosis by preventing bone absorption. In this application, the third generation zoledronic acid was analyzed using a non-suppressor type anion chromatography column, IC I-524A.

Sample: 100 µL
1. Zoledronic acid monohydrate 2 mg/mL
dissolved in H2O

Column       : Shodex IC I-524A (4.6 mm I.D. x 100 mm)
Eluent       : 0.47 mL of Formic acid in 2500 mL of Water, pH3.5
               (adjusted with 2 N NaOH aq.)
Flow rate    : 1.0 mL/min
Detector     : RI
Column temp. : 35 °C

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Operation Manual / Certificate of Analysis

Operation Manuals and Certificate of Analysis / Inspection Certificate for the following products can be downloaded here.

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