Tranexamic acid is a synthetic derivative of the amino acid lysine. When tranexamic acid is used internally it has hemostatic action, and when used externally on skin it has whitening properties. In this application, tranexamic acid was analyzed by Asahipak NH2P-40 2D, a polymer-based amino column under HILIC mode. Hydrophilic compounds are retained at a high concentration of acetonitrile under HILIC mode conditions. This is advantageous for high sensitivity analysis by LC/MS.
*Sales of Asahipak NH2P-40 2D used in this application is discontinued. Please consider trying Asahipak NH2P-50 2D.
Sample: 5 μL
Tranexamic acid 5 ng/mL (in H2O/CH3CN=25/75)
- Column
- ：Shodex Asahipak NH2P-40 2D (2.0 mm I.D. x 150 mm)
- Eluent
- ：20 mM HCOONH4 aq./CH3CN=25/75
- Flow rate
- ：0.2 mL/min
- Detector
- ：ESI-MS (SIM Positive)
- Column temp.
- ：30 ℃
Sample Name Index
Operation Manual / Certificate of Analysis
Operation Manuals and Certificate of Analysis / Inspection Certificate for the following products can be downloaded here.
Product Name Index
Applications
- Amino Acids (2) (NN-814)
- Amino Acids (3) (P-421S)
- Amino Acids (4) (YS-50)
- Amino Acids (5) (YS-50)
- Histidine and 1-Methylhistidine
- Separation of Carcinogenic Tryptophan Pyrolysis Products (ES-502C 7C)
- LC/MS Analysis of Essential Amino Acids (NH2P-40 2D)
- LC/MS Analysis of Citrulline (NH2P-40 2D)
- LC/MS Analysis of GABA (NH2P-40 2D)
- Simultaneous Analysis of Saccharides, Organic Acids and Amino Acids with LC/MS (VG-50 2D)
- Simultaneous Analysis of Hydrophilic Substances in Energy Drink with LC/MS (VG-50 2D)
- Simultaneous Analysis of Amino Acids with LC/MS (VC-50 2D)
- Analysis of Theanine (NH2P-50 4E)
- Analysis of Theanine in Supplement (NH2P-50 4E)
- Analysis of GABA in a Supplement (NH2P-50 4E)
- Effects of Organic Solvent Concentration on HILIC Mode (NH2P-50 4B)