Etelcalcetide hydrochloride is a synthetic peptide consisting of eight amino acid residues. It is used for a treatment of secondary hyperparathyroidism. Etelcalcetide was analyzed by PROTEIN KW-802.5, an aqueous SEC (GFC) column. An etelcalcetide hydrochloride derived main peak and a peak assumed to be the sample matrix origin were observed.
Sample: 20 μL
- 1.Etelcalcetide hydrochloride 5 mg/mL
- Column
- ：Shodex PROTEIN KW-802.5 (8.0 mm I.D. x 300 mm)
- Eluent
- ：H2O/CH3CN/TFA=750/250/1
- Flow rate
- ：0.5 mL/min
- Detector
- ：UV (225 nm)
- Column temp.
- ：25 ℃
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