The Chinese Pharmacopoeia 2025 Edition*, Part IV “Human Blood Products,” the high‑performance liquid chromatography method for the determination of sugars and sugar alcohols specifies the use of a column packed with a styrene–divinylbenzene copolymer–based cation‑exchange resin (hydrogen form) with dimensions of 7.8 mm (I.D.) x 300 mm (L) and a particle size of 9 or 8 µm**. SUGAR SH1011 column confirmed the requirements were met.

System suitability requirements

Resolution between the maltose peak and the sulfosalicylic acid peak: > 1.5
Tailing factor of maltose: 0.95–1.50
Correlation coefficient of linear regression (R²): ≥ 0.999

*The version at the time of the application acquisition.
**Chinese Pharmacopoeia 2025 edition allows changes in column dimensions, packing material, and particle sizes. 

Sample: 20 µL

1. 1.Sulfosalicylic acid 7.5 mg/mL
2. 2.Maltose 10 mg/mL

Sample: 20 µL

1. 2.Maltose 30 mg/mL
2. 3.Glucose 15 mg/mL
3. 4.Sorbitol 15 mg/mL

Sample: 20 µL

1. 5.Sucrose 30 mg/mL

***Since sucrose partially decomposes when analyzed at or above 25 ℃, the calibration curve should be constructed using the peak area including the decomposition products.