High Sensitive Analysis of Perchloric Acid and Oxyhalides by LC/MS (JJ-50 2D)

In Japan, monitoring of perchloric acid is required for drinking water quality control. The advisory level is assigned at 0.025 mg/L (April 2011 in Japan). In this application, RSpak JJ-50 2D was used for an LC/MS analysis of perchloric acid and oxyhalides. JJ-50 is modified with quaternary ammonium functional group and it works as a multimode column (reversed phase + anion exchange). By optimizing mobile phase composition and flow rate for LC/MS, 0.1 ug/L perchloric acid can be detected under SIM mode.


Sample : 5 μL
Standards
Tap water

ClO4-, Perchlorate
ClO3-, Chlorate
BrO3-, Bromate
ClO2-, Chlorite
Cl-, Chloride

Column       : Shodex RSpak JJ-50 2D (2.0 mm I.D. x 150 mm)
Eluent       : 50 mM Ammonium formate aq./CH3CN=25/75
Flow rate    : 0.2 mL/min
Detector     : ESI-MS (SIM)
Column temp. : 30 °C

Sample Name Index

Operation Manual / Certificate of Analysis

Operation Manuals and Certificate of Analysis / Inspection Certificate for the following products can be downloaded here.

Product Name Index

Applications