Eudragit L100 (methacrylic acid copolymer L) is used as an additive (coating agent) in pharmaceuticals and it was analyzed with GPC KF-806M, a column used for organic solvent type SEC (GPC). A mixture of THF and acetone was used as the eluent. PMMA (polymethyl methacrylate) is suitable as a calibration standard for calculating molecular weight distribution because a good calibration curve can be obtained with the THF/acetone eluent.
Sample : 20 μL
Methacrylic acid copolymer L
(EUDRAGIT® L 100) 0.4 % (v/v)
Column : Shodex GPC KF-806M (8.0 mm I.D. x 300 mm) Eluent : THF/Acetone=50/50 Flow rate : 1.0 mL/min Detector : RI Column temp. : 40 °C
Sample Name Index
Operation Manual / Certificate of Analysis
Operation Manuals and Certificate of Analysis / Inspection Certificate for the following products can be downloaded here.
Product Name Index
Applications
- Polystyrene Standards (10) (Toluene Eluent)
- Polystyrene Standards (19) (DMAc Eluent) (KF-806L)
- Polystyrene Standards (20) (NMP Eluent) (KF-806L)
- Polystyrene Standards (22) (DMAc Eluent) (LF-804)
- Silicone Oil (Toluene Eluent) (K-806M)
- Dimethyl Silicone Oil (Toluene Eluent)
- Rubber (Tluene Eluent)
- Melamine-Formaldehyde Resin Prepolymers (Mixed Solvent Eluent)
- Epoxy Resin (3) (Mixed Solvent Eluent)
- p-Cresol Formaldehyde Resol Resin (Mixed Solvent Eluent)
- Phenol Formaldehyde Novolac Resin (Mixed Solvent Eluent)
- Poly(-N,N-Dimethylaminomethyl Styrene) (2) (Comparison of Various Eluent Condition)
- Lignin (LF-804)
- Xylan (LF-804)
- Polyamic Acid (1) (LF-804)
- Polyamic Acid (2) (LF-804)
- Polyamic Acid (3) (LF-804)
- Cellulose (KD-806M)
- Biodegradable Polymer (1) (Poly(Lactic-co-Glycolic Acid)) (GF-7M HQ)
- Biodegradable Polymer (5) (Poly(Lactic-co-Glycolic Acid)) (KF-804L)
- Pullulan Standards (8) (LF-804)
- Poly(Ethylene Oxid) and Poly(Ethylene Glycol) Standards (2) (LF-804)
- Poly(Methyl Methacrylate) (2) (Eluent: Methyl Ethyl Ketone) (LF-804)
- Ammonio Methacrylate Copolymer (GF-510 HQ)
- Absolute Molecular Weight Determination of PMMA (LB-802.5)
Applications (Related Information)
- Calibration Curves for KF-806L (Various Eluents: PS)
- Calibration Curve for LF-804 (DMAc Eluent: PEG, PEO)
- Calibration Curve for LF-804 (DMAc Eluent: PS)
- Calibration Curve for LF-804 (NMP Eluent: PEG, PEO)
- Calibration Curve for LF-804 (NMP Eluent: PS)
- Calibration Curve for LF-804 (Methyl Ethyl Ketone Eluent: PMMA)
- Calibration Curve for LF-804 (DMSO/DMF Eluent: Pullulan)
- Calibration Curves for GF-HQ Series (Methanol Eluent: PEG, PEO)
- Calibration Curves for GF-HQ Series (Acetone Eluent: PMMA)