The monograph below became official on August 1, 2022.

Potassium preparation drugs supplement potassium in the body and improve the symptoms such as weakness and nausea caused by lack of potassium.
According to the United States Pharmacopeia and the National Formulary Pharmacopeial Forum (PF 45(5)*), potassium ion assay of the potassium bicarbonate and potassium chloride effervescent tablets for oral solution should be carried out with an ion chromatography and a column filled with L76 packing material using, and meets following requirements. The use of a cation column, IC YK-421, confirmed the requirements were met.

Resolution of potassium and calcium ions: ≥ 3.0
Tailing factor: ≤ 2.0%
Relative standard deviation (RSD): ≤ 2.0%

*The version at the time of the application acquisition.

Sample: 20 μL
30 µg/mL of Potassium chloride and 15 µg/mL of Magnesium in H₂O

1.  

Sample: 20 μL
30 µg/mL of Potassium chloride in H₂O

1.