Zanamivir is a neuraminidase inhibitor, and it is effective in the treatment of influenza caused by influenza A and B viruses. According to the United States Pharmacopeia and the National Formulary (USP 37-NF 32*), "ASSAY" for "Zanamivir" should be carried out with a column filled with L82 packing material. The Asahipak NH2P-50 4E, a column filled with L82 packing material, confirmed the requirements were met.

System suitability requirementsResolution between zanamivir and talo-zanamivir (Resolution solution): ≥ 1.5
Relative standard deviation (RSD) (Standard solution): ≤ 1.5%

*The version at the time of the application acquisition.

Sample: 20 µL
(Resolution solution) 2.5 µg/mL of talo-zanamivir and 0.05 mg/mL of zanamivir in eluent

1. 1.Zanamivir
2. 2.talo-Zanamivir