According to the United States Pharmacopeia and the National Formulary (USP-NF 2024 Issue 3*), the assay of erythritol, should be carried out with a column packed with L17 packing material and meets following requirements. The SUGAR SH1011, an ion exclusion chromatography column, confirmed the requirements were met.
System suitability requirements
Resolution (0.05-mg/mL each USP Erythritol RS and glycerol): ≥ 2.0
Relative standard deviation (RSD) for 50-mg/mL USP Erythritol RS: ≤ 2.0%
*The version at the time of the application acquisition.
Sample: 10 µL
(System suitability solution) 0.05 mg/mL of each in H2O
- 1.USP Erythritol RS
- 2.Glycerol

Sample: 10 µL
(Standard solution) 50 mg/mL USP Erythritol RS in H2O
- 1.USP Erythritol RS

- Column
- :Shodex SUGAR SH1011 (8.0 mm I.D. x 300 mm)
- Eluent
- :0.01 % H2SO4 aq.
- Flow rate
- :0.8 mL/min
- Detector
- :RI
- Column temp.
- :70 ℃
Sample Name Index
Operation Manual / Certificate of Analysis
Operation Manuals and Certificate of Analysis / Inspection Certificate for the following products can be downloaded here.
Product Name Index
Applications
- Analysis of Saccharides in Coconut Water (NH2P-50 4E)
- Elution Volume of Saccharides and Sugar Alcohols (NH2P-50 4E)
- Sugar Alcohols (1) (SC1211)
- Sugar Alcohols (2) (NH2P-50)
- Sugar Alcohols (3)
- Saccharides and Sugar Alcohols (1) (SZ5532)
- Saccharides and Sugar Alcohols (2) (SP0810)
- Saccharides and Sugar Alcohols (3) (SP0810)
- Saccharides and Sugar Alcohols (4) (SC1011)
- Saccharides and Sugar Alcohols (5) (SZ5532)
- Saccharides and Sugar Alcohols (6) (NH2P-50)
- Saccharides and Amino Acids (1) (SC1011)
- Saccharides and Amino Acids (2) (SC1211)
- Saccharides and Amino Acids (3) (KS-801)
- Saccharides and Amino Sugars (2) (NH2P-50 4E)
- Saccharides and Amino Sugars (3) (SC1011)
- Xilitol in Tablet Candy
- Apple Juice (NH2P-50 4E)
- Apple Juice (SC1011)
- Sake (Japanese Rice Wine)
- Effects of Acetonitrile Concentration in Analysis of Sugar Alcohols
- Amino Sugars (SB-802.5 HQ)
- Soft Drink Containing Erythritol (NH2P-50 4E)
- Palatinit (SP0810, SC1011, SZ5532)
- Analysis of Pinitol (SP0810)
- Analysis of Meglumine (NN-814)
- LC/MS/MS Analysis of Meglumine (VC-50 2D)
- Analysis of Meglumine (YS-50)
- Separation of myo-Inositol and D-chiro-Inositol (SZ5532)
- Separation of Taurine and Inositol (NH2P-50 4E)
- Analysis of Hydrogenated Maltose Starch Syrup According to Japanese Pharmaceutical Excipients Method (KS-801)
- Analysis of Mannitol According to Pharmacopeia Method (SC1011-7F)
- Analysis of Mannitol Compounded Injection According to USP-NF Method (SP0810)
- Analysis of myo-Inositol According to EP Method (SC1011-7F)
- Analysis of Xylitol According to USP-NF Method (SP0810)
- Analysis of Sorbitol According to USP-NF Method (SP0810 8C)
- Analysis of Maltitol According to USP-NF Method (SP0810 8C)
- Comparison of Sensitivity of NH2P Polymer-based Column and Silica-based Amino Column with ELSD
- Analysis of Erythrose and Erythritol (VG-50 4E)
- Analysis of D-chiro-Inositol (KS-801)