According to the United States Pharmacopeia and the National Formulary (USP-NF 2024 Issue 3*), the assay of erythritol, should be carried out with a column packed with L17 packing material and meets following requirements. The SUGAR SH1011, an ion exclusion chromatography column, confirmed the requirements were met.

System suitability requirements

Resolution (0.05-mg/mL each USP Erythritol RS and glycerol): ≥ 2.0
Relative standard deviation (RSD) for 50-mg/mL USP Erythritol RS: ≤ 2.0%

*The version at the time of the application acquisition.

Sample: 10 µL
(System suitability solution) 0.05 mg/mL of each in H₂O

1. 1.USP Erythritol RS
2. 2.Glycerol

Sample: 10 µL
(Standard solution) 50 mg/mL USP Erythritol RS in H₂O

1. 1.USP Erythritol RS