ORpak CDBS-453で分割可能な光学異性体

β−シクロデキストリンの特性により、下記の光学異性体と類似した化学構造を有する化合物はORpak CDBS-453を用いて分離できる可能性が高くなります。

Epinephrine	Terbutaline	Norphenylephrine
α=1.15, Rs=2.1 Eluent: A	α=1.14, Rs=2.2 Eluent: D	α=1.11, Rs=1.9 Eluent: D
Oxyphencyclimine	Trihexyphenidyl	Promethazine
α=1.11, Rs=1.6 Eluent: C	α=1.14, Rs=1.8 Eluent: C	α=1.08, Rs=1.2 Eluent: E
Trimipramine	Brompheniramine	Homatropine
α=1.13, Rs=1.9 Eluent: E	α=1.35, Rs=4.2 Eluent: B	α=1.14, Rs=1.7 Eluent: E
Benzoin	Zopiclone	Nefopam
α=1.15, Rs=1.8 Eluent: E	α=1.22, Rs=1.8 Eluent: B	α=1.35, Rs=4.9 Eluent: E
Oxazepam	Hexobarbital	Norlaudanosoline
α=1.20, Rs=2.4 Eluent: B	α=1.18, Rs=2.1 Eluent: A	α=1.24, Rs=2.1 Eluent: B
Chlortharidone	Indapamide	Efaroxan
α=1.29, Rs=3.8 Eluent: B	α=1.18, Rs=2.2 Eluent: D	α=1.11, Rs=1.8 Eluent: E
2-Phenoxypropionic acid	Propanolol
α=1.15, Rs=2.4 Eluent: B	α=1.11, Rs=1.5 Eluent: E

Eluent A : 1% CH3CN + 99% (0.05% CH3COOH + 0.2M NaCl) in H2O
Eluent B : 10% CH3CN + 90% (1.1% CH3COOH + 0.2M NaCl) in H2O
Eluent C : 30% CH3CN + 70% (1.1% CH3COOH + 0.2M NaCl) in H2O
Eluent D : 10% CH3CN + 90% (1.4% CH3COOH + 0.7% (C2H5)3N + 0.2M NaCl) in H2O
Eluent E : 25% CH3CN + 75% (1.4% CH3COOH + 0.7% (C2H5)3N + 0.2M NaCl) in H2O