• HOME
  • Product Search
  • Application Search
  • Distributors
  • Support

LC/MS Analysis of Statins (ODP2 HP-2B)

Print

Statins are a group of drugs used to lower cholesterol level by inhibiting HMG-CoA reductase. Seven statins were simultaneously analyzed by LC/MS method using a polymer-based reversed phase column, ODP2 HP-2B.


Sample : 100ng/mL each, 5μL
Pravastatin
Pitavastatin
Fluvastatin
Atorvastatin
Mevastatin
Lovastatin
Simvastatin


Column       : Shodex ODP2 HP-2B (2.0mmI.D. x 50mm)
Eluent       : (A); 10mM Ammonium formate aq.
               (B); CH3CN
               (B%) 10% (0min) -> 0% (3min) -> 5% (13min) -> 5% (20min)
Flow rate    : 0.2mL/min
Detector     : ESI-MS (SIM)
Column temp. : 40°C

Contact us